Core Facilities at Biochemistry : Biochemistry Optical Core; Biophysics Instrumentation Facility


The Core Facilities at Biochemistry encompass four open access service facilities and instrumentation cores that provide state-of-the-art instrumentation, technical expertise, and education to researchers at the University of Wisconsin and beyond.    


Core Facilities and Shared Resourse

  • UW-Madison Cryo-EM Facility

  • UW-Madison Crystallography Core

  • Biochemistry Optical Core

  • Biophysics Instrumentation Facility


Calendar Access

Please click on the calendar link below that you would like to schedule on.  After logging in, you will be taken directly to that calendar.  If you do not have an iLab account, please click here to request one.


Biochemistry Optical Core 


Nikon A1R+ Confocal




Biophysics Instrumentation Facility


All calendars for Biophysics Instrumentation Facility


Overview of Services 

Biochemistry Optical Core

The Biochemistry Optical Core (BOC) provides access to state-of-the-art instrumentation for confocal, epi-fluorescent, TIRFM, and super-resolution light microscopy.   We are currently located in the Biochemical Science Complex in the Department of Biochemistry at the University of Wisconsin-Madison.  Our mission is to enhance basic and translation research by providing training and expertise on basic and advanced light microscopy techniques.   Additionally, expertise and advice is available for the design of experiments, grants, and manuscripts involving these techniques as well as consultation on image analysis processes.  

For information regarding instrument training and use, please contact Elle Grevstad 


Biophysics Instrumentation Facility


The Biophysics Instrumentation Facility (BIF) is part of the Department of Biochemistry at the University of Wisconsin-Madison and is located in Room B1408 on the Ground Floor of the Biochemical Sciences Building. The facility provides access to state of the art instrumentation focused on the study of conformations, activities and assembly of biological and other macromolecules. While each instrument provides distinct insight, the ensemble enables a thorough characterization of, structure, function and interaction of biological assemblies. For information regarding instrument training and use, please contact BIF staff (Darrell McCaslin or Dan Stevens). 

The Facility is always on the lookout for new users from departments across campus. If you are interested in having us speak at a group or departmental meeting about our capabilities, please contact Dan Stevens. Introductory slides about the BIF are available here.



Biochemistry Core Facilities

Elle Grevstad, Director


Phone: 608.263.2436 


Biochemistry Optical Core

Elle Grevstad, Optical Core Director 


Phone: 608.263.2436 


Biophysical Instrumentation Facility

Dan Stevens, Assistant Scientist


Phone: 608.890.1946


Darrel McCaslin, Biophysics InstrumentationFacility Manager


Phone: 608.262.8074


Location and hours of operation

Hours Location

Monday - Friday

9 am - 5 pm *


*access granted 24/7 for                      

trained individuals


HFD Biochemical Sciences Building

440 Henry Mall

Madison, WI 53704


Biochemistry Optical- Room 5404a

Biophysical Instrumentation- Room B1408

Links and Resources

  1. Biochemistry at UW Madison
  2. Biochemistry Optical Core
  3. Biophysics Instrumentation Facility

Available Equipment and Resources

Biochemistry Optical (4)
Biophysical Instrumentation (3)
Biophysical Instrumentation - Calorimetry (3)
Biophysical Instrumentation - Concentration (2)
Biophysical Instrumentation - Light Scattering (2)
Biophysical Instrumentation - Mass Spectrometry (1)
Biophysical Instrumentation - Other (3)
Biophysical Instrumentation - PCR (2)
Biophysical Instrumentation - Plate Readers (1)
Biophysical Instrumentation - Spectroscopy (3)