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Core Facilities at Biochemistry : Biochemistry Optical Core; Biophysics Instrumentation Facility; Collaborative Crystallography Core


The Core Facilities at Biochemistry encompass four open access service facilities and instrumentation cores that provide state-of-the-art instrumentation, technical expertise, and education to researchers at the University of Wisconsin and beyond.    


Core Facilities and Shared Resourse

  • UW-Madison Cryo-EM Facility

  • Collaborative Crystallography Core

  • Biochemistry Optical Core

  • Biophysics Instrumentation Facility


Calendar Access

Please click on the calendar link below that you would like to schedule on.  After logging in, you will be taken directly to that calendar.


Biochemistry Optical Core 


Nikon A1R+ Confocal



Elements Image Analysis Station


Biophysics Instrumentation Facility


All calendars for Biophysics Instrumentation Facility


Collaborative Crystallograpghy Core


JANSi UVEX-P Microscope

TTP LabTech Mosquito

Overview of Services 

Biochemistry Optical Core

The Biochemistry Optical Core (BOC) provides access to state-of-the-art instrumentation for confocal, epi-fluorescent, TIRFM, and super-resolution light microscopy.   We are currently located in the Biochemical Science Complex in the Department of Biochemistry at the University of Wisconsin-Madison.  Our mission is to enhance basic and translation research by providing training and expertise on basic and advanced light microscopy techniques.   Additionally, expertise and advice is available for the design of experiments, grants, and manuscripts involving these techniques as well as consultation on image analysis processes.  

For information regarding instrument training and use, please contact Peter Favreau.


Biophysics Instrumentation Facility


The Biophysics Instrumentation Facility (BIF) is part of the Department of Biochemistry at the University of Wisconsin-Madison and is located in Room 4420 of the Biochemical Sciences Building. The facility provides access to state of the art instrumentation focused on the study of conformations, activities and assembly of biological and other macromolecules. While each instrument provides distinct insight, the ensemble enables a thorough characterization of, structure, function and interaction of biological assemblies. For information regarding instrument training and use, please contact BIF staff (Darrell McCaslin or Dan Stevens). 

The Facility is always on the lookout for new users from departments across campus. If you are interested in having us speak at a group or departmental meeting about our capabilities, please contact Dan Stevens


Collaborative Crystallography Core


The Collaborative Crystallography Core (CCC) is part of the Department of Biochemistry at the University of Wisconsin–Madison and is located in Rooms 2211, 2268 and 2305 on the 2nd floor of the Hector F. DeLuca Biochemical Sciences Building. The crystallography core provides instrumentation for setting up crystallization experiments and imaging the results. Expertise in construct design, protein production, crystallization, data collection and grant development is available.

For information regarding instrument training and use, please contact Craig Bingman.



Peter Favreau, Biochemistry Optical Core

Craig Bingman, UW- Crystallography Facility

Darrell McCaslin, Biophysics Instrumentation Facility 

Dan Stevens, Biophysics Instrumentation Facility



Location and hours of operation

Hours Location

Monday - Friday

9 am - 5 pm *


*access granted 24/7 for                      

trained individuals


HFD Biochemical Sciences Building

440 Henry Mall

Madison, WI 53704


Biochemistry Optical- Room 5404a

Biophysical Instrumentation- Room 4420

Links and Resources

  1. Biochemistry at UW Madison
  2. Biochemistry Optical Core
  3. Biophysics Instrumentation Facility
  4. Collaborative Crytallography Core

Services and Daily Rates

Search available services: View: by category alphabetically
Services (1)
Supplies (4)

Available Equipment and Resources

Biochemistry Optical (4)
Biophysical Instrumentation (2)
Biophysical Instrumentation - Calorimetry (3)
Biophysical Instrumentation - Concentration (2)
Biophysical Instrumentation - Light Scattering (2)
Biophysical Instrumentation - Mass Spectrometry (1)
Biophysical Instrumentation - Other (3)
Biophysical Instrumentation - PCR (2)
Biophysical Instrumentation - Plate Readers (1)
Biophysical Instrumentation - Spectroscopy (3)
Cryo-EM (1)
Retired Instruments (1)