CPCT Genomics Core

Overview of Services

The Center for Personalized Cancer Therapy (CPCT) Genomics Core was established in 2015 to enable UMass Boston investigators and academic and industry collaborators to carry out basic and translational genomics research. The Core leverages cutting-edge technologies and next-generation sequencing capabilities for research and clinical applications. We help investigators and clinicians analyze samples, identify genetic variants contributing to disease risk, and reveal complex mechanisms involved in human disease.

The core offers cost-effective massively parallel sequencing with the Illumina HiSeq 2500 (v4 upgraded) and MiSeq systems; Next-generation sequencing library preparation from RNA and DNA and nucleic acid quality assessments using Bioanalyzer, Tapestation, Nanodrop and Qubit assays. Additional instruments include a NanoString nCounter Analysis System, a Biomek FXp automated workstation, and a QuantStudio 12K Flex Real-Time PCR System.

The Center for Personalized Cancer Therapy is a collaborative venture between the University of Massachusetts Boston and the Dana Farber/Harvard Cancer Center (DF/HCC) and is funded by the Massachusetts Life Sciences Center. To learn more about the CPCT and its partnership with DF/HCC, click here.

Leadership

Jill Macoska PhD | Core Director

Susan Patalano | Core Manager

Location and hours of operation

Links and Resources

1. CPCT Genomics Core
2. Illumina Sequence Coverage Calculator
3. HiSeq Coverage and Number of Reads per Lane
4. MiSeq Coverage and Number of Reads per Lane
5. Nanostring Panels
   
6. CPCT website

Acknowledging the Core

We request that you properly acknowledge the CPCT Genomics Core in all publications and grant applications. Example statement for publication is as follows:  

“[Service] was performed by the CPCT Genomics Core at the University of Massachusetts Boston.”

Please let us know when a work is published or a grant proposal is submitted/awarded which references our core. This will allow us to demonstrate our value to the research community.
The CPCT Genomics Core is partially supported by Massachusetts Life Sciences Center.

Shipping Instructions

Ship To:

CPCT/Susan Patalano
ISC/4th fl/4630
UMass Boston
100 Morrissey Blvd.
Boston, MA 02125

Please tell us when you ship samples to our core and provide tracking information.  Wrap your samples in two layers of water tight plastic bags.  Pack in enough dry ice to last 72 hours.  The packaging must be constructed to allow the release of carbon dioxide gas and prevent rupturing due to gas pressure build-up.  Ensure it is NOT air tight.  A class 9 label is required.  

Do not send tubes in flat envelopes.

Directions

The CPCT Genomics Core is located at UMass Boston in the Integrated Sciences Complex (ISC), 4th floor, rm 4630.  The hallway is locked.  Call  617-287-6578 to be let in once you are on the 4th floor.

Directions and Parking information:

Parking on campus is limited.  Many commuters park at the overflow lot at Bayside (200 Mt. Vernon Street) when fall and spring semesters are in session.  Take the free rt 3 shuttle from Bayside to the Clark stop.  Walk up the nearby, outside staircase and enter the Quinn building which will be in front of you and towards the right side.  Stay on this floor level and follow the signs to the ISC.  There is a catwalk connecting Quinn to the ISC.  Once you enter the ISC from the catwalk, walk to the right and take the elevator to the 4th floor.  The room number is 4630.  Please call the phone number above to be let in.

Directions to Bayside lot:

Driving from the South:

Take I-93 North to exit 14 (Morrissey Blvd./JFK Library).  The campus will be on your right.  Stay on Morrissey Blvd. and drive 1/2 mile past the campus entrance.  Take a right onto Mt. Vernon St. at the next set of lights.  The Bayside lot will be on the left.  Park and take the free shuttle bus to the campus, Clark stop.  See above for directions to our lab from the Clark stop.

Driving from the North:

Take I-93 South to exit 15 (Columbia Rd/JFK Library).  Take a left at the bottom of the exit ramp.  Enter the rotary and take the second right onto Day Blvd, then sharp right onto Mt. Vernon St.  Turn left to stay on Mt. Vernon St.  The Bayside lot will be on your left.  Park and take the free shuttle bus to campus, Clark stop.  See above for directions to our lab from the Clark stop.

Public Transportation to Campus:

Take the MBTA's Red Line to JFK/UMass subway station.  Exit the station to the busway area below.  Then take one of the free shuttle buses to the UMass Boston campus.  

Contacts