Gladstone Genomics Core


The Gladstone Genomics Core provides services to support the next-generation sequencing needs of the scientific research community.

Next-generation sequencing (NGS) experiments enable cutting-edge genomics, transcriptomics, and epigenomics studies. We offer several types of library preparations for NGS, including quality control steps and sequencing, and we are constantly looking to expand our range of services with the latest techniques. Gladstone Genomics Core offer services to Gladstone Institutes, UCSF, external no profit and external, for profit companies. Consultation prior to experiment design, close interactions with the Gladstone Bioinformatics Core and willingness to explore ad-hoc techniques make the Gladstone Genomics Core a crucial resource for researchers.

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Services available at the Gladstone Genomics Core


  • Illumina NextSeq 500 (Currently very rapid turn around time)
  • Illumina MiSeq

Single Cell RNA-seq (scRNA-seq)

  • 10x Genomics Single Cell Gene Expression
  • 10x Genomics Single Cell V(D)J

NGS Library Preparation

  • RNA-seq (stranded and non-stranded RNA-seq)
  • small RNA-seq
  • ChIP-seq
  • NGS library prep

QC and Sample Preparation

  • DNA and RNA isolation
  • Agilent Bioanalyzer
  • Covaris S2 Sonicator
  • NanoDrop
  • Qubit

The Core is aware that sometimes it is not possible to get good quality RNA and DNA, and we are willing to work with researchers to process difficult samples.  In fact, the Core has had considerable success with generating sequencing data from less than ideal samples.  However, investigators are responsible for all costs associated with failed reactions due to poor quality or degraded starting material. 


Gladstone Institutes, 1650 Owens Street, San Francisco, CA 94158 - USA

Genomics Core: 5th floor, lab bays 5N-5P (Mission Bay Campus)

Directions and Parking: 

Hours of Operation

Monday - Friday,   8:30 am - 4:30 pm or by appointment


Name Role Phone Email Location
Natasha Carli, PhD
Genomics Core Director

Jim McGuire
Senior Research Technologist

Yanxia Hao
Senior Research Technologist



Name Description